Evidence comparison

Reishi (Ganoderma lucidum) vs Cordyceps

How they actually compare on the evidence — trial volume, literature, mechanism, and our honest confidence grade. Higher counts reflect research attention, not proof of superiority.

Eastern · Tonic Herbs

Reishi (Ganoderma lucidum)

灵芝

72Confidence

Human RCT evidence

RCTs: 29
Meta: 18
Trials: 48

Key active: Ganoderic acids & triterpenes (botanical extract)

Primarily preclinical (model-organism + animal) for aging; clinical data mostly outside longevity endpoints

Reishi is a multi-compound botanical (triterpenes, polysaccharides). Recent animal work links ganoderate compounds and α-Klotho modulation to lifespan extension and aging-related markers.

Full Reishi (Ganoderma lucidum) evidence →

Eastern · Tonic Mushroom

Cordyceps

冬虫夏草

70Confidence

Human RCT evidence

RCTs: 33
Meta: 21
Trials: 28

Key active: Cordycepin & polysaccharides (botanical extract)

Mostly preclinical for aging; small human trials on exercise and fatigue

Cordyceps is a multi-compound fungus (cordycepin, adenosine, polysaccharides) studied for AMPK activation, mitochondrial ATP support, and immune modulation; most longevity-relevant data is preclinical.

Full Cordyceps evidence →

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Informational only — not medical advice or a recommendation to take either. Trial and literature counts are registry/database matches and include endpoints beyond longevity. See each ingredient page for sources.