Evidence library · East meets West
Longevity ingredients, backed by evidence — not marketing.
Every ingredient links to real clinical trials, peer-reviewed literature, and the verified suppliers who carry it. We show mixed and null results on purpose.
The most-studied tea catechin, linked to lifespan and healthspan in models via AMPK, sirtuin and FOXO pathways.
The classic Chinese longevity mushroom; emerging research connects its triterpenes to anti-aging and α-Klotho signalling.
A foundational Qi tonic whose cycloastragenol fraction (TA-65) is studied for telomerase activation — with honestly mixed human evidence.
The archetypal adaptogen; ginsenoside-rich extracts extend healthspan in model organisms via mitochondrial and stress pathways.
An alkaloid from Chinese herbs (Coptis / Huang Lian) with human RCTs on metabolic health and an AMPK/sirtuin longevity rationale.
A turmeric polyphenol with one of the largest trial bases in nutraceuticals, studied for inflammation, autophagy and healthspan — bioavailability is the catch.
The headline NAD+ booster of the longevity world — human trials show it raises blood NAD+ and may support physical function.
The grape-and-knotweed polyphenol that launched the sirtuin era of longevity research.
A fasting-mimicking polyamine that triggers autophagy and extends lifespan across species.
A prized Chinese tonic fungus studied for stamina, mitochondrial energy, and immune modulation.
The classic Chinese longevity berry, rich in polysaccharides and carotenoids studied for eye, immune, and oxidative health.
The “five-flavor berry,” an adaptogen studied for liver protection, stress resilience, and cellular defense.
“Southern ginseng,” a Chinese herb whose gypenosides activate AMPK — the metabolic longevity pathway.
A famous Chinese longevity tonic — with a real, honest caveat: reports of liver toxicity.
An edible mushroom studied for nerve-growth-factor support and cognitive healthspan.
A medicinal mushroom whose PSK/PSP polysaccharides have the strongest clinical record in immune oncology support.
A high-altitude adaptogen with human trials on fatigue and stress — and a foothold in both Eastern and Western tradition.
Among the most-trialed supplements in medicine, with emerging evidence on biological-age slowing.
One of the most evidence-backed supplements anywhere — for muscle, and increasingly for the aging brain.
A foundational hormone-vitamin where deficiency is common and consequential for aging health.
A plant flavonoid and leading senolytic candidate — clearing “zombie” senescent cells in animal models.
A widespread dietary flavonoid, studied as a senolytic partner (with dasatinib) and anti-inflammatory.
A gut-derived metabolite that triggers mitophagy — with human trials on muscle and mitochondrial function.
A glutathione-restoring amino-acid pair with promising small trials on oxidative stress and aging markers.
A more bioavailable cousin of resveratrol, often paired with NAD precursors in longevity formulas.
The mitochondrial electron carrier that declines with age and statin use — with cardiovascular trial support.
A cofactor for hundreds of enzymes, widely under-consumed, tied to sleep, metabolic, and DNA-repair pathways.
An amino acid whose decline was linked to aging in a high-profile 2023 study — with human causality still open.
The single most reproducible lifespan-extending molecule in animals — a prescription drug under off-label longevity study.
The diabetes drug at the center of the longevity debate — and the TAME trial designed to test aging itself.