Origin & tradition
Turmeric (姜黄) is used across Chinese and Asian medicine as a warming, blood-moving and anti-inflammatory herb.
Eastern tradition · Herbal Wellness
Curcumin (Turmeric) 姜黄素
A turmeric polyphenol with one of the largest trial bases in nutraceuticals, studied for inflammation, autophagy and healthspan — bioavailability is the catch.
Why longevity buyers care
Key active: Curcumin (diferuloylmethane).
Curcumin is a polyphenol acting on NF-κB-driven inflammation, autophagy and senescence pathways. The honest caveat: native curcumin has poor oral bioavailability, so formulation matters and many trials use enhanced forms.
Evidence summary
What the research actually says
80Evidence confidence
Extensive human-trial evidence512 randomized controlled trials · 456 meta-analyses / systematic reviews
Very large trial base for inflammation; longevity endpoints mechanistic; bioavailability-limited
Curcumin is a polyphenol acting on NF-κB-driven inflammation, autophagy and senescence pathways. The honest caveat: native curcumin has poor oral bioavailability, so formulation matters and many trials use enhanced forms.
388registered clinical trials reference this intervention
2selected from 2+ PubMed papers (longevity / aging angle)
Key active: Curcumin (C21H20O6) · ChEMBL CHEMBL140 · max clinical phase 3 · natural product
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed, compound data from EMBL-EBI ChEMBL. Counts auto-refresh weekly; last checked 2026-06-06. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
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