Origin & tradition
Yun Zhi (云芝) is used in Chinese medicine as an immune and liver tonic; its extract PSK is an approved adjuvant in parts of Asia.
Eastern tradition · Functional Mushroom
Turkey Tail (Yunzhi) 云芝
A medicinal mushroom whose PSK/PSP polysaccharides have the strongest clinical record in immune oncology support.
Why longevity buyers care
Key active: PSK / PSP polysaccharides (botanical extract).
PSK and PSP are immunomodulating polysaccharides with human oncology-adjuvant trials; longevity relevance is via immune resilience (immunosenescence), not direct lifespan data.
Evidence summary
What the research actually says
68Evidence confidence
Human RCT evidence52 randomized controlled trials · 8 meta-analyses / systematic reviews
Human immune/oncology-adjuvant trials; aging link via immunity
PSK and PSP are immunomodulating polysaccharides with human oncology-adjuvant trials; longevity relevance is via immune resilience (immunosenescence), not direct lifespan data.
48registered clinical trials reference this intervention
2selected from 2+ PubMed papers (longevity / aging angle)
Key active: PSK / PSP polysaccharides (botanical extract) — a multi-compound botanical extract, so activity is not reducible to a single molecule.
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-06-06. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
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